RAY PUN - PUBLICATIONS

click on a bullet to see the abstract (usually from PubMed)

	LaSarge, C.L., Pun, R.Y.K., Gu, Z., Santos, V.R., and Danzer, S.C. (2019) Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors? Exp. Neurol. 321, 113029.
	Arafa, S.R., LaSarge, C.L., Pun, R.Y.K., Khademi, S., and Danzer, S.C. (2019) Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth. Exp. Neurol. 311, 125-134.
	Santos, V.R., Pun, R.Y.K., Arafa, S.R., LaSarge, C.L., Rowley, S., Khademi, S., Bouley, T., Holland, K.D., Garcia-Cairasco, N., and Danzer, S.C. (2017) PTEN deletion increases hippocampal granule cell excitability in male and female mice. Neurobiol. Dis. 108, 339-351.
	LaSarge, C.L., Pun, R.Y., Muntifering, M.B., and Danzer, S.C. (2016) Disrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells. Neurobiol. Dis. 96, 105-114.
	Gross, C., Yao, X., Engel, T., Tiwari, D., Xing, L., Rowley, S., Danielson, S.W., Thomas, K.T., Jimenez-Mateos, E.M., Schroeder, L.M., Pun, R.Y.K., Danzer, S.C., Henshall, D.C., and Bassell, G.J. (2016) MicroRNA-mediated downregulation of the potassium channel Kv4.2 contributes to seizure onset. Cell Rep. 17, 37-45.
	Jiang, Y., Pun, R.Y., Peariso, K., Holland, K.D., Lian, Q., and Danzer, S.C. (2015) Olfactory bulbectomy leads to the development of epilepsy in mice. PLoS ONE 10, e0138178.
	Castro, O.W., Santos, V.R., Pun, R.Y., McKlveen, J.M., Batie, M., Holland, K.D., Gardner, M., Garcia-Cairasco, N., Herman, J.P., and Danzer S.C. (2012) Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy. PLoS ONE 7, e46044.
	Pun, R.Y., Rolle, I.J., Lasarge, C.L., Hosford, B.E., Rosen, J.M., Uhl, J.D., Schmeltzer, S.N., Faulkner, C., Bronson, S.L., Murphy, B.L., Richards, D.A., Holland, K.D., and Danzer S.C. (2012) Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy. Neuron 75, 1022-1034.
	Santos, V.R., de Castro, O.W., Pun, R.Y., Hester, M.S., Murphy, B.L., Loepke, A.W., Garcia-Cairasco, N., and Danzer, S.C. (2011) Contributions of mature granule cells to structural plasticity in temporal lobe epilepsy. Neuroscience 197, 348-357.
	Murphy, B.L., Pun, R.Y., Yin, H., Faulkner, C.R., Loepke, A.W., and Danzer, S.C. (2011) Heterogeneous integration of adult-generated granule cells into the epileptic brain. J. Neurosci. 31, 105-117.
	McDole, J.R., Danzer, S.C., Pun, R.Y., Chen, Y., Johnson, H.L., Pirko, I., and Johnson, A.J. (2010) Rapid formation of extended processes and engagement of Theiler's virus-infected neurons by CNS-infiltrating CD8 T cells. Am. J. Pathol. 177, 1823-1833.
	Walter, C., Murphy, B.L., Pun, R.Y., Spieles-Engemann, A.L., and Danzer, S.C. (2007) Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells. J. Neurosci. 27, 7541-7552.
	Schmit, J.M., Riley, M.A., Dalvi, A., Sahay, A., Shear, P.K., Shockley, K.D., and Pun, R.Y. (2006) Deterministic center of pressure patterns characterize postural instability in Parkinson's disease. Exp. Brain Res. 168, 357-367.
	Pun, R.Y.K. and Kleene, S.J. (2004) An estimate of the resting membrane resistance of frog olfactory receptor neurones. J. Physiol. 559, 533-540.
	Pun, R.Y.K. and Kleene, S.J. (2003) Contribution of cyclic-nucleotide-gated channels to the resting conductance of olfactory receptor neurons. Biophys. J. 84, 3425-3435.
	Pun, R.Y.K. and Kleene, S.J. (2002) Outward currents in olfactory receptor neurons activated by odorants and by elevation of cyclic AMP. Cell Biochem. Biophys. 37, 15-26.
	Nickell, W.T., Pun, R.Y.K., Bargmann, C.I., and Kleene, S.J. (2002) Single ionic channels of two Caenorhabditis elegans chemosensory neurons in native membrane. J. Membr. Biol. 189, 55-66.
	Matthew, E., Pun, R., Simonich, M., Iwamoto, H., and Dedman, J. (1999) Cyclosporin A protects lung function from hyperoxic damage. Am. J. Physiol. 276 (Lung Cell. Mol. Physiol. 20), L786-L795.
	Kobayashi, S., Conforti, L., Pun, R.Y.K., and Millhorn, D.E. (1998) Adenosine modulates hypoxia-induced responses in rat PC12 cells via the A2A receptor. J. Physiol. 508, 95-107.
	Liu, L.H., Paul, R.J., Sutliff, R.L., Miller, M.L., Lorenz, J.N., Pun, R.Y.K., Duffy, J.J., Doetschman, T., Kimura, Y., MacLennan, D.H., Hoying, J.B., and Shull, G.E. (1997) Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3. J. Biol. Chem. 272, 30538-30545.
	Cui, Y., Su, Y.-R., Rutkowski, M., Reif, M., Menon, A.G., and Pun R.Y.K. (1997) Loss of protein kinase C inhibition in the beta-T594M variant of the amiloride-sensitive Na+ channel. Proc. Natl. Acad. Sci. USA 94, 9962-9966.
	Tam, E.S., Ferguson, D.G., Bielefeld, D.R., Lorenz, J.N., Cohen, R.M., and Pun, R.Y.K. (1997) Norepinephrine-mediated calcium signaling is altered in vascular smooth muscle of diabetic rat. Cell Calcium 21, 143-150.
	Su, Y.-R., Rutkowski, M.P., Klanke, C.A., Wu, X., Cui, Y., Pun, R.Y.K., Carter, V., Reif, M., and Menon, A.G. (1996) A novel variant of the beta-subunit of the amiloride-sensitive sodium channel in African Americans. J. Am. Soc. Nephrol. 7, 2543-2549.
	Kleene, S.J. and Pun, R.Y.K. (1996) Persistence of the olfactory receptor current in a wide variety of extracellular environments. J. Neurophysiol. 75, 1386-1391.
	Pun, R.Y.K. and Lecar, H. (1995) Patch-clamp techniques and analysis. In: Cell Physiology Source Book (N. Sperelakis, ed.). San Diego: Academic Press, pp. 279-292.
	Pun, R.Y.K., Kleene, S.J., and Gesteland, R.C. (1994) Guanine nucleotides modulate steady-state inactivation of voltage-gated sodium channels in frog olfactory receptor neurons. J. Membr. Biol. 142, 103-111.
	Doupnik, C.A. and Pun, R.Y.K. (1994) G-protein activation mediates prepulse facilitation of Ca2+ channel currents in bovine chromaffin cells. J. Membr. Biol. 140, 47-56.
	Cui, Y. and Pun, R.Y.K. (1994) Angiotensin II suppresses Na+ currents in bovine adrenal chromaffin cells. Peptides 15, 67-72.
	Behbehani, M.M., Liu, H., Jiang, M., Pun, R.Y.K., and Shipley, M.T. (1993) Activation of serotonin1A receptors inhibits midbrain periaqueductal gray neurons of the rat. Brain Res. 612, 56-60.
	Doupnik, C.A. and Pun, R.Y.K. (1992) Cyclic AMP-dependent phosphorylation modifies the gating properties of L-type Ca2+ channels in bovine adrenal chromaffin cells. Pflügers Arch. 420, 61-71.
	Gillis, K.D., Pun, R.Y.K., and Misler, S. (1991) Single cell assay of exocytosis from adrenal chromaffin cells using "perforated patch recording". Pflügers Arch. 418, 611-613.
	Pun, R.Y.K. and Gesteland, R.C. (1991) Somatic sodium channels of frog olfactory receptor neurones are inactivated at rest. Pflügers Arch. 418, 504-511.
	Gillis, K.D., Pun, R.Y.K., and Misler, S. (1991) Long-term monitoring of depolarization-induced exocytosis from adrenal medullary chromaffin cells and pancreatic islet B-cells using "perforated patch recording". Ann. N.Y. Acad. Sci. 635, 464-467.
	Ferguson, D.G., Lewis, S.A., and Pun, R.Y.K. (1991) In vitro synaptic transmission in sympathetic neuron-vascular smooth muscle co-cultures. Adv. Exp. Med. Biol. 304, 507-515.
	Pixley, S.K. and Pun, R.Y.K. (1990) Cultured rat olfactory neurons are excitable and respond to odors. Brain Res. Dev. Brain Res. 53, 125-130.
	Pun, R.Y.K. and Behbehani, M.M. (1990) A rapidly inactivating Ca2+-dependent K+ current in pheochromocytoma cells (PC12) of the rat. Pflügers Arch. 415, 425-432.
	Behbehani, M.M., Pun, R.Y.K., Means, E.D., and Anderson, D.K. (1990) Thyrotropin-releasing hormone has profound presynaptic action on cultured spinal cord neurons. Synapse 6, 169-174.
	Pun, R.Y.K. (1988) Voltage clamping with single microelectrodes: comparison of the discontinuous mode and continuous mode using the Axoclamp 2A amplifier. Mol. Cell. Biochem. 80, 109-120.
	Pun, R.Y.K., Neale, E.A., Guthrie, P.B., and Nelson, P.G. (1986) Active and inactive central synapses in cell culture. J. Neurophysiol. 56, 1242-1256.
	Nelson, P.G., Pun, R.Y.K., and Westbrook, G.L. (1986) Synaptic excitation in cultures of mouse spinal cord neurones: Receptor pharmacology and behaviour of synaptic currents. J. Physiol. 372, 169-190.
	Pun, R.Y.K., Marshall, K.C., Hendelman, W.J., Guthrie, P.B., and Nelson, P.G. (1985) Noradrenergic responses of spinal neurons in locus-coeruleus-spinal cord co-cultures. J. Neurosci. 5, 181-191.
	Litzinger, M.J., Nelson, P.G., and Pun, R.Y.K. (1985) Effects of nitrendipine on the voltage-sensitive calcium channel in mammalian sensory neurons. J. Neurosci. Res. 14, 415-422.
	Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., Stoker, M.J., and Szabadi, E. (1983) Differential antagonists effects of haloperidol on excitatory responses of cortical neurones to phenylephrine, noradrenaline and dopamine. Neuropharmacology 22, 945-952.
	Nelson, P.G., Marshall, K.C., Pun, R.Y.K., Christian, C.N., Sheriff, W.H., Macdonald, R.L., and Neale, E. (1983) Synaptic interactions between mammalian central neurons in cell culture. II. Quantal analysis of EPSPs. J. Neurophysiol. 49, 1442-1458.
	Macdonald, R.L., Pun, R.Y.K., Neale, E., and Nelson, P.G. (1983) Synaptic interactions between mammalian central neurons in cell culture. I. Reversal potential for excitatory postsynaptic potentials. J. Neurophysiol. 49, 1428-1441.
	Pun, R.Y.K. (1982) Studies on synaptic transmission in spinal cord cultures: a comparison of postsynaptic actions of classical neurotransmitters with the peptides. Peptides 3, 249-257.
	Marshall, K.C., Pun, R.Y.K., Hendelman, W.J., and Nelson, P.G. (1981) A coeruleo-spinal system in culture. Science 213, 355-357.
	Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi, E. (1981) Comparison of the effects of methoxamine with those of noradrenaline and phenylephrine on single cerebral cortical neurones. Br. J. Pharmacol. 73, 47-54.
	Bevan, P., Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi E. (1981) Electro-osmotic and iontophoretic release of noradrenaline from micropipettes. Experientia 37, 296-297.
	Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi, E. (1981) A procedure for comparing the mobilities of unlabeled drugs used in microelectrophoresis experiments. J. Pharmacol. Methods 5, 67-73.
	Bevan, P., Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi, E. (1979) The relative contribution of iontophoresis and electro-osmosis to the electrophoretic release of noradrenaline from multibarrelled micropipettes. Br. J. Pharmacol. 67, 478P-479P.
	Bevan, P., Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi, E. (1979) Does DPI [(3,4-dihydroxy-phenylamino)-2-imidazoline] act at dopamine receptors on cortical neurones? Br. J. Pharmacol. 66, 126P.
	Bevan, P., Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi, E. (1979) The action of microelectrophoretically applied (3,4-dihydroxy-phenylamino)-2-imidazoline (DPI) on single cortical neurones. Br. J. Pharmacol. 65, 701-706.
	Bevan, P., Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi, E. (1978) Comparison of the responses of single cortical neurones to tyramine and noradrenaline: effects of desipramine. Br. J. Pharmacol. 63, 651-657.
	Bevan, P., Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi, E. (1978) Responses of single cortical neurones to noradrenaline and dopamine. Neuropharmacology 17, 611-617.
	Bevan, P., Bradshaw, C.M., Pun, R.Y.K., Slater, N.T., and Szabadi, E. (1978) The effect of desipramine on neuronal responses to tyramine and noradrenaline in the cerebral cortex. Br. J. Pharmacol. 62, 402P-403P.